Adenine phosphoribosyltransferase deficiency is an inherited problem that affects the kidneys and urinary system. Later, recurrent kidney and urinary system stones can lead to troubles with kidney function starting as early as mid- to late childhood years. Around fifty percent of people with APRT deficiency first experience signs and symptoms of the problem in their adult years. Other signs and symptoms of APRT deficiency triggered by kidney and urinary tract stones include fever, urinary system infection, blood in the urine, abdominal pains, nausea or vomiting, and throwing up. Without therapy, kidney function can decline, which may lead to end-stage renal disease. When the kidneys are no longer able to filter fluids and waste items from the body effectively, esrd is a deadly failure of kidney function that occurs. It is estimated that 15 to 20 percent of people with APRT deficiency do not have any signs or symptoms of the problem.
* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions
** If you believe that content on the Plex is summarised improperly, please, contact us, and we will get rid of it quickly; please, send an email with a brief explanation.