Allopurinol

Summarized by Plex Health
Last Updated: 02 May 2022
xanthine oxidase inhibitor, allopurinol, prevented oxidative stress, fibrosis, and myocardial damage in isoproterenol induced aged rats. "xanthine oxidase inhibitor, allopurinol, prevented oxidative stress, fibrosis, and myocardial damage in isoproterenol induced aged rats.", by Sagor MA, Tabassum N, Potol MA, Alam MA. fig1: Hematoxylin and Eosin staining showed inflammatory cell infiltration and necrosis in left ventricle of heart section of rats treated with ISO. Control rats showed normal architecture with very well-shaped cardiomyocytes in left ventricle of...

Patients with large tumor masses, leukemia, or gout arthritis in some cases receive allopurinol which is a medicine used to decrease the level of uric acid in the blood. Allopurinol is readily available in the following forms: A white 100-mg tablet computer taken by mouth; An orange 300-mg tablet computer taken by mouth; A white 20 mg/mL liquid taken by mouth; A clear liquid provided by vein. Call the medical professional right away if you have any one of the following side effects: Chills, fever, muscle mass pains, or aching throat; Joint pain or muscle aches; Nausea and vomiting together with a skin rash; Sudden decrease in amount of urine, pain while urinating, or blood in urine; Skin rash, redness, itching, or hives; Trouble breathing; Yellow skin or eyes. If you are getting IV allopurinol and have pain or inflammation at the injection website, report it right away to your nurse. If allopurinol is taken with a dish or right after a vomiting, nausea and dish might be decreased. Antacids may decrease how well allopurinol works. If you generate too much uric acid or your kidneys do not filter enough out, it can accumulate and cause little, sharp crystals to develop in and around your joints. Allopurinol is used to deal with gout and kidney rocks. Allopurinol comes as 100mg and 300mg tablets and is only available on prescription. Allopurinol is additionally recognized by the trademark name Zyloric and Uricto. Allopurinol lowers the amount of uric acid made by your body's cells. Allopurinol can be taken by adults and often children. Talk with a medical professional or pharmacologist if you: have ever before had an allergic reaction to allopurinol or any other medication; are of Han Chinese, Thai or Korean beginning; have troubles with your liver or kidneys; currently have an attack of gout; have thyroid troubles. Allopurinol can lower blood cells that aid your body battle infections. Stop utilizing this medication and get emergency situation clinical assistance if you have signs of an allergy to allopurinol or a severe skin reaction. To reduce your risk of kidney stones forming, drink 8 to 10 complete glasses of liquid everyday, unless your doctor informs you otherwise. If you are incapable to take the medication by mouth, Allopurinol injection is provided as a mixture into a capillary. Even if you have no symptoms, tests can help your medical professional identify if allopurinol works. You might have gout pain attacks regularly when you first begin taking this medicine oral.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
135401907C5H4N4O136.11C1=NNC2=C1C(=O)NC=N2C1=NNC2=C1C(=O)NC=N2InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)OFCNXPDARWKPPY-UHFFFAOYSA-N1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one-0.7136.03851076136.0385107670.119002301000000001
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