Alpha-1 antitrypsin deficiency is an inherited disorder that may cause lung disease and liver disease. People with alpha-1 antitrypsin deficiency usually develop the first signs and symptoms of lung disease between ages 25 and 50. Individuals with alpha-1 antitrypsin deficiency are in jeopardy of developing a type of liver cancer called hepatocellular cancer. In uncommon cases, people with alpha-1 antitrypsin deficiency develop a skin problem called panniculitis, which is characterized by solidified skin with agonizing lumps or spots. Hereditary changes that cause AAT might suggest that the body's liver cells make inadequate or no AAT, or make a form of AAT that does not work well. Everybody has 2 duplicates of the gene for AAT and receives one duplicate of the genetics from each parent. Individuals with AATD have one normal copy and one harmed duplicate, or they have two broken duplicates. Most people who have one normal gene can create sufficient alpha-1 antitripsin to live healthy lives, specifically if they do not smoke.
* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions
** If you believe that content on the Plex is summarised improperly, please, contact us, and we will get rid of it quickly; please, send an email with a brief explanation.