Alpha-1 Antitrypsin Deficiency

Summarized by Plex Health
Last Updated: 02 May 2022
a comparative ultrastructural and molecular biological study on chlamydia psittaci infection in alpha-1 antitrypsin deficiency and non-alpha-1 antitrypsin deficiency emphysema versus lung tissue of patients with hamartochondroma. "a comparative ultrastructural and molecular biological study on chlamydia psittaci infection in alpha-1 antitrypsin deficiency and non-alpha-1 antitrypsin deficiency emphysema versus lung tissue of patients with hamartochondroma.", by Theegarten D, Anhenn O, Hotzel H, Wagner M, Marra A, Stamatis G, Mogilevski G, Sachse K. F1: Histology of alpha-1 antitrypsin deficiency emphysema. In alpha-1 antitrypsin deficiency, advanced panacinar destruction of the lung parenchyma and accumulation of macrophages (A, hematoxylin eosin, original magnification ×40), as well as severe acute and chronic...

Alpha-1 antitrypsin deficiency is an inherited disorder that may cause lung disease and liver disease. People with alpha-1 antitrypsin deficiency usually develop the first signs and symptoms of lung disease between ages 25 and 50. Individuals with alpha-1 antitrypsin deficiency are in jeopardy of developing a type of liver cancer called hepatocellular cancer. In uncommon cases, people with alpha-1 antitrypsin deficiency develop a skin problem called panniculitis, which is characterized by solidified skin with agonizing lumps or spots. Hereditary changes that cause AAT might suggest that the body's liver cells make inadequate or no AAT, or make a form of AAT that does not work well. Everybody has 2 duplicates of the gene for AAT and receives one duplicate of the genetics from each parent. Individuals with AATD have one normal copy and one harmed duplicate, or they have two broken duplicates. Most people who have one normal gene can create sufficient alpha-1 antitripsin to live healthy lives, specifically if they do not smoke.

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

** If you believe that content on the Plex is summarised improperly, please, contact us, and we will get rid of it quickly; please, send an email with a brief explanation.

*** If you want us to remove all links leading to your domain from Plex.page and never use your website as a source of the "Online Knowledge", please contact us using a corporate email and we will remove everything in 10 business days.

logo

Plex Page is a Biology & Health Sciences "Online Knowledge Base," where a machine summarizes all the summaries.