Alpha Thalassemia

Summarized by Plex Health
Last Updated: 02 May 2022

Alpha thalassemia is a blood disorder that reduces the production of hemoglobin. Hemoglobin is the protein in red blood cells that lugs oxygen to cells throughout the body. In people with the characteristic features of alpha thalassemia, a reduction in the amount of hemoglobin protects against sufficient oxygen from reaching the body's tissues. Affected individuals also have a shortage of red cell, which can cause pale skin, weak point, fatigue, and more serious complications. Two types of alpha thalassemia can cause illness. The more severe type is known as hemoglobin Bart hydrops fetalis syndrome, which is also called Hb Bart disorder or alpha thalassemia major. Hb Bart syndrome is defined by hydrops fetalis, a condition in which excess liquid accumulates in the body before birth. Hb Bart syndrome can additionally cause serious complications for women while pregnant, including dangerously high blood pressure with swelling, premature shipment, and abnormal bleeding.

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