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Amantadine

Summarized by Plex Health
Last Updated: 02 May 2022
amantadine induced corneal edema in a patient with primary progressive freezing of gait. "amantadine induced corneal edema in a patient with primary progressive freezing of gait.", by Kim YE, Yun JY, Yang HJ, Kim HJ, Kim MK, Wee WR, Jeon BS. f1-jmd-6-2-34-3: A: Slit-lamp examination of the anterior segment showing amantadine induced corneal edema. B: Resolution at 1 month after the cessation of amantadine. Corneal opacity and punctate epithelial erosion improved....

Amantadine hydrochloride is assigned chemically as 1-adamantanamine hydrochloride. It has the following structural formula: Amantadine hydrochloride is a secure white or virtually white crystalline powder, openly soluble in water and soluble in alcohol and in chloroform. Amantadine hydrochloride has pharmacological activities as both an anti-Parkinson and an antiviral medicine. Amantadine hydrochloride is available as 100 mg pills for oral administration. Non-active components: microcrystalline cellulose, hydroxypropyl cellulose, croscarmellose salt, colloidal silicon dioxide, magnesium stearate, gelatin, titanium dioxide, FD&C Blue # 1, FD&C Red # 40. The non-volatile components of inscribing ink are shellac, propylene glycol, potassium hydroxide and titanium oxide. Meets USP Dissolution Test 2. Amantadine is also used to deal with or protect against flu A in children and adults. If you received a nasal influenza vaccine in the previous 14 days, you should not use amantadine. Heat stroke has happened in people taking amantadine. Deaths have happened in people with kidney issues whose dosage was too high for their kidney function. People with Parkinson's disease might have a higher risk of skin cancer. If you take amantadine to treat influenza A, begin taking the medication within 24 to 48 hours after flu symptoms begin. It may be given alone or in combination with other medications for Parkinson's disease. By enhancing muscle mass control and minimizing stiffness, this medicine allows more normal motions of the body as the disease symptoms are lowered. Amantadine is additionally used to deal with stiffness and shakiness triggered by specific medicines that are used to deal with nervous, mental, and emotional problems. Amantadine is an antiviral medicine. It may be given alone or together with flu shots. Amantadine will not help colds, other types of influenza, or other virus infections. This medicine is readily available only with your doctor's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
2130C10H17N151.25C1C2CC3CC1CC(C2)(C3)NC1C2CC3CC1CC(C2)(C3)NInChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2DKNWSYNQZKUICI-UHFFFAOYSA-Nadamantan-1-amine2.4151.136099547151.1360995472614401101100000001
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