Amitriptyline

Summarized by Plex Health
Last Updated: 03 May 2022

Amitriptyline is a tricyclic antidepressant with sedative results. Amitriptyline is a prescription medicine used to treat symptoms of clinical depression. Do not use amitriptyline if you have used an MAO prevention in the previous 14 days. Some young people have thoughts about self-destruction when first taking an antidepressant. Your family or other caregivers need to additionally look out to changes in your mood or symptoms. Keep using the drug as directed and tell your medical professional if your symptoms do not improve. You might begin to really feel better after 1 or 2 weeks, yet it can take 6 weeks for amitriptyline to work as a medicine. Contact your doctor prior to beginning to take amitriptyline if you: have ever had a sensitive reaction to amitriptyline or any other medication; have a heart trouble, amitriptyline can make some heart troubles worse; have unusual blood disorder called porphyria; have liver or kidney troubles; have epilepsy, amitriptyline can increase seizures or fits; have ever taken any medicines for clinical depression, some antidepressants used seldom can influence the way amitriptyline works; are pregnant, trying to end up being pregnant, or breastfeeding; have an eye problem called glaucoma, amitriptyline can increase the pressure in your eye; have thoughts about damaging on your own or ending your life; have type 1 or type 2 diabetes mellitus. Amitriptyline might change your blood sugar degree if you have diabetes mellitus. You might require to take a various dose of amitriptyline or prevent taking the medicine if your body breaks down the medicine slower or faster than normal. Quiting the medicine too swiftly might cause these symptoms: Dizzy feeling; Nausea, throwing up; Headache; Feeling more exhausted than normal; Sleep issues; Feeling irritable; This medicine might cause you to really feel woozy and sluggish. If you are taking amitriptyline more than one-time a day and you neglect to take a dosage, adhere to these standards: If your next dose is not due for more than 4 hrs, take the missed dose as soon as you remember.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
2160C20H23N277.4CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3KRMDCWKBEZIMAB-UHFFFAOYSA-NN,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine5277.183049738277.1830497383.233100132100000001
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