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Antidepressant For Hot Flashes

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Last Updated: 18 January 2022

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Study Has Found That Antidepressant Effexor Eases Hot Flashes Just As Well As Hormone Replacement Therapy. There are two types of antidepressant SSRIs and SNRIs. Effexor is SNRI. Research Was Published Online On May 26 2014 By JAMA Internal Medicine. Read abstract of Low - Dose Estradiol and Serotonin - Norepinephrine Inhibitor Venlafaxine For Vasomotor Symptoms: randomized Clinical Trial. Menopausal symptoms such as hot flashes and night sweats can dramatically reduce quality of life for some women. Hot Flashes are also are known side effect of hormonal therapy medicines used treat Breast Cancer. Doctors call Hot and night sweats Vasomotor Symptoms. Some women use hormone therapy to ease these symptoms. But research has shown that HRT increases Breast risk in women who haven't been diagnose. Hrt also increases risk of Breast Cancer coming back in women who have been diagnosed with disease. Hrt is not recommended for who have been diagnosed with Breast Cancer. Undiagnosed Women who have severe menopausal symptoms need to weigh benefits of HRT against its risks. It is not clear if any of 339 women in this study had been diagnosed with Breast Cancer or were at high risk for disease. Women have at least Hot Flashes per day and most have about eight. Women were randomly assigned to receive of three treatments daily for 8 weeks: Low - Dose Estrogen - only HRT 75 mg Effexor placebo After 8 weeks, number of Hot Flashes per day most women having dropped from eight to four - 50 percentage decrease. Hrt reduces Flashes by 52. 9 percentage . Effexor reduced Hot by 47. 6 percentage . Placebo reduces Flashes by 28. 6 percentage . Difference In Hot Flash Reduction Between HRT And Effexor Wasnt Significant, Which Means That It Could Have Happened By Chance And Wasnt Necessarily Because Of Difference In Medicine. In 2013, US Food and Drug Administration approved Low - Dose formula of another antidepressant, Paxil, under brand name Brisdelle, to treat Hot Flashes. Paxil is SSRI. Fda approval was on research comparing Paxil to placebo pill. Study Review Here Is First Time Researchers Have Compared Antidepressants To HRT To Treat Hot Flashes. Other research has suggested other antidepressants may help ease Hot Flashes, including SSRIs: Prozac, Lexapro and Celexa. Some of these antidepressants may cause problems for taking tamoxifen. Enzyme Called CYP2D6 Helps Tamoxifen Work In Body. Some research has shown that women with abnormal genes that block their body's ability to produce CYP2D6 do get same benefits from tamoxifen as women who produce CYP2D6. Other research has shown that some medicines - including Antidepressants Paxil and Prozac - interfere with how CYP2D6 works and might reduce tamoxifen's effectiveness against Breast Cancer. Still, subject is controversial and not all experts agree that lack of or taking antidepressants reduces tamoxifen effectiveness.

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* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Answer

Review Of Literature Suggests That Treatment With SSRIs Or SNRIs Reduces Frequency And Severity Of Hot Flashes In Menopausal And Post - Menopausal Women. Studies demonstrate that paroxetine, citalopram and escitolapram were most effective SSRIs, and venlafaxine was most effective first line SNRI, with desvenlafaxine as second option. Most Common Side Effects Reported For Both SSRIs And SNRIs Are Nausea And Constipation, With Most Resolved Within First Week Of Treatment. Snris has been associated with increased pressure in some patients and should be used with caution in women with hypertension. Women with history of breast cancer and taking tamoxifen should avoid SSRIs, which have been shown to interfere with tamoxifen metabolism. Snris is safest drug for this population. Treatment choice should be patient - specific and begin with lowest dose available.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Continued

New YORK - for about third of women taking antidepressants to treat menopause symptoms, hot flashes and night sweats will return after discontinuing drug, according to NEW study. It is important people to understand that. Benefit of treatment is related to duration of treatment, says Dr. Hadine Joffe, lead author of study. But that should discourage women trying antidepressants if they want to, she add. Just because symptoms come back after you stop it doesnt mean it does make big difference when you take it, said Joffe, who is associate professor of psychiatry at Harvard Medical School and director of Research in Center for Women's Mental Health at Massachusetts General Hospital. Escitalopram, antidepressant sold under brand name Lexapro, is not approved to treat menopause symptoms, but physicians may prescribe it because some - though not all - studies have found it can reduce number and severity of hot flashes. It has moderate effect, Joffe told Reuters Health. Drugs do not eliminate hot flashes, but can make very meaningful improvement in somebody's life. Antidepressants of same type as Lexapro, called selective serotonin reuptake inhibitors, are also used to treat menopause symptoms. Joffe said there have not been enough studies determine just how long women should take antidepressants to treat hot flashes, nor whether symptoms return once they stop treatment. To address second question, she and her colleagues asked 200 women to take 10 or 20 milligrams day of Lexapro for eight weeks. Teams final analysis include 76 women who show at least 20 percent improvement on drugs, instance, dropping from 10 hot flashes day down to eight or fewer. After two - month treatment period, women stop taking pills and researchers track their symptoms for another three weeks. Team Was Also Careful To Screen For Withdrawal Symptoms From Drugs Itself. Menopause symptoms return for about third of women who had seen improvement on drugs. Results Were Similar Whether Women Had Reported Experiencing Less Severe Symptoms While On Drugs Or Had Said They Felt Less Bothered By Their Symptoms During Treatment. Among 49 women who they had benefited on all three symptom measures - number, severity and bothersomeness - 44 percent experienced relapse within three weeks of discontinuing drug. For most of women, symptoms rebound to about same levels as before treatment. Among women who didnt relapse, symptoms dropped about 9. 5 days before to 4. 4 per three weeks after stopping. Joffe said it is impossible to say whether this group would experience greater return symptoms later on, or would continue to see reduction. We only look within weeks of stopping medication, she say. We dont know if we study them for six or six months.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Sources

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

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