Antineutrophil Cytoplasmic Antibodies Test

Summarized by Plex Health
Last Updated: 02 May 2022

This test searches for antineutrophil cytoplasmic antibodies in your blood. Antibodies are proteins that your immune system makes to combat foreign substances like infections and germs. ANCAs attack healthy and balanced cells recognized as neutrophils by blunder. Autoimmune vasculitis causes inflammation and swelling of the capillary. Blood vessels bring blood from your heart to your organs, tissues, and other systems, and after that back again. Inflammation in the capillary can cause significant health problems. Problems vary depending on which capillary and body systems are affected. There are 2 major sort of ANCA. Each targets a specific protein inside white blood cells: pANCA, which targets a protein called MPO; cANCA, which targets a protein called PR3. The test can show whether you have one or both types of antibodies. This can help your healthcare provider identify and treat your disorder. Other names: ANCA antibodies, cANCA pANCA, cytoplasmic neutrophil antibodies, serum, anticytoplasmic autoantibodies An ANCA test is usually used to discover if you have a type of autoimmune vasculitis. They all cause inflammation and swelling of capillary, however each type affects different blood vessels and components of the body. Types of autoimmune vasculitis include: Granulomatosis with polyangiitis, formerly called Wegener's disease. Eosinophilic granulomatosis with polyangiitis, previously called Churg-Strauss disorder. An ANCA test might additionally be used to keep an eye on therapy of these disorders. Your health treatment provider may order an ANCA test if you have symptoms of autoimmune vasculitis. Your symptoms might also affect one or more specific body organs in your body.

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