Arrhythmogenic Right Ventricular Cardiomyopathy

Summarized by Plex Health
Last Updated: 02 May 2022
arrhythmogenic right ventricular cardiomyopathy/dysplasia. "arrhythmogenic right ventricular cardiomyopathy/dysplasia.", by Thiene G, Corrado D, Basso C. F1: Graphic showing the various causes of juvenile sudden cardiac death in Northeast Italy. ARVC/D ranks second (13%) after atherosclerotic coronary artery disease. ARVC = arrhythmogenic right ventricular cardiomyopathy; ATS CAD = atherosclerotic coronary artery...

Arrhythmogenic right ventricular cardiomyopathy is an inherited heart disease in which the muscular tissue of the right ventricle of the heart is replaced by fat and/or mark tissue. Individuals with ARVC commonly develop abnormal heart rhythms called arrhythmias, which can increase the risk of sudden heart attack or fatality. Often, abrupt cardiac death can be the first sign of ARVC. ARVC is brought on by genetic mutations in genes that instruct proteins to link one heart cell to the next. There is some evidence that ARVC might be brought on by an infection of the heart muscle. A specific with an autosomal dominant condition has a 50% risk to pass the mutation on to each child. Parents of a specific with an autosomal recessive condition each carry one mutated copy of the genetics and are referred to as carriers. When two carriers of an autosomal recessive condition have children, each child has a 25% risk to acquire mutations and be affected. Hereditary testing can aid figure out which pattern of inheritance an affected individual has.

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