Aspergillosis

"medpix case - allergic bronchopulmonary aspergillosis (abpa)", by Original Source: Steve Kao; Author: Steve Kao (National Capital Consortium); Approved By: David S. Feigin, M.D. (Johns Hopkins Hospitals);. PA radiograph demonstrates a well marginated oval shaped opacity overlying the right 7th posterior rib interspace, in mid-clavicular line. This opacity is within the anterior segment of the right upper lobe and represents a mucus-plugged...

Aspergillosis is an infection triggered by a type of mold and mildew. One kind is allergic bronchopulmonary aspergillosis, a problem where the fungus causes allergic respiratory symptoms comparable to bronchial asthma, such as coughing and hissing, but does not in fact damage and get into tissue. Another sort of aspergillosis is invasive aspergillosis. This infection usually influences people with damaged body immune systems due to cancer, AIDS, leukemia, body organ transplantation, radiation treatment, or other conditions or events that decrease the variety of normal white blood cells. Invasive aspergillosis most commonly affects the lungs, but can cause infection in many other organs and can spread out throughout the body. Aspergilloma, a growth that develops in an area of previous lung disease such as tuberculosis or lung abscess, is a third sort of aspergillosis. This type of aspergillosis is composed of a tangled mass of fungus fibers, blood clots, and white blood cells. The fungus ball progressively increases the size of, damaging lung tissue in the procedure, yet usually does not spread to other areas. Treatment is started immediately if the infection is widespread or the individual shows up seriously ill. Voriconazole is presently first-line treatment for invasive aspergillosis and is usually given intravenously. There are other antifungal drugs that can be used to treat invasive aspergillosis in patients who can not take voriconazole or that have not replied to voriconazole. Whenever feasible, immunosuppressive medicines must be discontinued or decreased. A fungus round usually does not call for therapy unless bleeding into the lung tissue is associated with the infection, then surgical treatment is needed. Antifungal agents do not help people with sensitive aspergillosis. Allergic aspergillosis is treated with prednisone taken by mouth.

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