Beckwith-Wiedemann Syndrome

Summarized by Plex Health
Last Updated: 10 May 2022

Beckwith-Wiedemann syndrome is a condition that influences many components of the body. In some children with Beckwith-Wiedemann syndrome, specific body components may grow abnormally large on one side of the body, leading to a irregular or asymmetric appearance. The signs and symptoms of Beckwith-Wiedemann syndrome vary among affected individuals. Some children with this condition are birthed with an opening in the wall of the abdominal area that enables the abdominal body organs to extend via the belly-button. Some babies with Beckwith-Wiedemann syndrome have an abnormally large tongue, which might hinder breathing, ingesting, and talking. Children with Beckwith-Wiedemann syndrome are at an increased risk of developing several types of cancerous and noncancerous tumors, particularly a form of kidney cancer called Wilms tumor and a form of liver cancer called hepatoblastoma. Most children and adults with Beckwith-Wiedemann syndrome do not have significant clinical troubles connected with the problem.

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