Belumosudil
Summarized by Plex Health
Last Updated: 03 May 2022
Belumosudil is used to treat persistent graft-versus-host disease after other at least two other therapies did not work. Belumosudil may also be used for objectives not listed in this drug guide. If you use other medications or have other medical conditions or allergic reactions, inform your physician. You may require to have an adverse maternity test prior to beginning this treatment. Both men and women using belumosudil needs to use reliable contraception to stop maternity. Belumosudil can damage a coming child if the mommy or daddy is using this medication. Keep using contraception for at least 1 week after your last dose. If a maternity occurs, tell your physician right away. Pregnancy might be less likely to occur while the daddy or the mom is using this medication. Due to the fact that the medication can harm an expected baby, both men and women ought to still use birth control to stop pregnancy. You will need constant blood tests to examine your liver function.
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PubChem - CovalentUnitCount
(Table source)| CID | MolecularFormula | MolecularWeight | CanonicalSMILES | IsomericSMILES | InChI | InChIKey | IUPACName | XLogP | ExactMass | MonoisotopicMass | TPSA | Complexity | Charge | HBondDonorCount | HBondAcceptorCount | RotatableBondCount | HeavyAtomCount | IsotopeAtomCount | AtomStereoCount | DefinedAtomStereoCount | UndefinedAtomStereoCount | BondStereoCount | DefinedBondStereoCount | UndefinedBondStereoCount | CovalentUnitCount |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 11950170 | C26H24N6O2 | 452.5 | CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC3=CC=CC=C3C(=N2)NC4=CC5=C(C=C4)NN=C5 | CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC3=CC=CC=C3C(=N2)NC4=CC5=C(C=C4)NN=C5 | InChI=1S/C26H24N6O2/c1-16(2)28-24(33)15-34-20-7-5-6-17(13-20)25-30-23-9-4-3-8-21(23)26(31-25)29-19-10-11-22-18(12-19)14-27-32-22/h3-14,16H,15H2,1-2H3,(H,27,32)(H,28,33)(H,29,30,31) | GKHIVNAUVKXIIY-UHFFFAOYSA-N | 2-[3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide | 4.8 | 452.19607403 | 452.19607403 | 105 | 678 | 0 | 3 | 6 | 7 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
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