Blindness

Summarized by Plex Health
Last Updated: 05 May 2022
the importance of selection in the evolution of blindness in cavefish "the importance of selection in the evolution of blindness in cavefish", by . Fig7: Many loci of small effect require stronger selection than a a single locus of large effect to evolve blindness in the face of immigration. a The equilibrium frequencies of the blindness allele for an...

CIRM funds many projects seeking to better comprehend diseases of blindness and to convert those explorations into new therapies. While there are numerous reasons for blindness, the leading root cause of all aesthetic impairment is age-related macular degeneration, which affects 1. 7 million Americans. All the research teams are seeking to use numerous forms of stem cells to rescue or change cells in the eye harmed or threatened by the diseases. Several groups are functioning on ways to recover vision for people with age-related macular degeneration. Other tasks are looking to preserve vision in patients with retinitis pigmentosa, and to recover clarity to the surface of eyes influenced by corneal disease. AMD affects 8 million Americans and accounts for over 50% of vision loss cases in white Americans. Some are using embryonic stem cells as a starting indicate generate new RPE cells. Others are utilizing stem cells obtained by reprogramming adult cells to be like embryonic cells, which can potentially come from the patients' themselves.

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