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Bone Marrow

Summarized by Plex Health
Last Updated: 01 May 2022
biopsy, bone marrow aspiration and "biopsy, bone marrow aspiration and", by Terese Winslow (Illustrator). Bone marrow aspiration and biopsy; drawing shows a patient lying face down on a table and a bone marrow needle being inserted into the hip bone. Inset shows the bone marrow needle being inserted through...

Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. The stem cells can become the red cell that bring oxygen with your body, the leukocyte that deal with infections, and the platelets that assist with blood clotting. With bone marrow disease, there are troubles with the stem cells or exactly how they develop: In leukemia, a cancer of the blood, the bone marrow makes abnormal white blood cells; In aplastic anemia, the bone marrow does not make red blood cells; In myeloproliferative disorders, the bone marrow makes a lot of white blood cells; Other diseases, such as lymphoma, can spread out into the bone marrow and affect the production of blood cells. Tests for bone marrow diseases include blood and bone marrow tests. In the severe stage, necrosis might be accompanied by acute inflammation or hemorrhage, while later phases or cases of subacute necrosis may be associated with increased varieties of macrophages around the necrotic area. Necrosis brought on by a blockage of the blood supply normally has well-delineated borders microscopically as an identifying feature. In a rat study to review the effects of feed limitation on common toxicologic specifications, extreme diet regimen restriction of only two weeks led to bone marrow necrosis and deterioration. Treatment includes radiation treatment and radiotherapy, and in some cases a bone marrow transplant from a healthy suitable person; Reticulum cell sarcoma of bone, a malignant tumour of the bone marrow, taking place more usually in males than in women. Blood transfusions might aid temporarily, but a severely affected person may die unless they obtain a transplant of normal bone marrow; Defective immune system, some children are born with a malfunctioning body immune system and are unable to eliminate disease.

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