Charcot-Marie-Tooth disease is a group of acquired conditions that damage the peripheral nerves. Charcot-Marie-Tooth disease is also understood as genetic motor and sensory neuropathy. The peripheral nerves are found outside the main central nervous system. The symptoms of Charcot-Marie-Tooth disease can vary from individual to person, even amongst relatives with the problem. Symptoms can differ depending on the type of CMT and even people with the same type can experience it differently. Signs that a little one may have CMT consist of: showing up accident-prone and unusually clumsy for their age; finding it hard to walk because they might have troubles raising their feet from the ground; their toes going down onward as they lift their feet. People with Charcot-Marie-Tooth disease commonly experience a decreased sensitivity to touch, warmth, and cold in the feet and lower legs, but occasionally feel hurting or melting feelings. People with CMT2 may develop amyotrophic side sclerosis, a problem identified by progressive muscle weakness, a loss of muscular tissue mass, and a failure to regulate movement. In forms of Charcot-Marie-Tooth disease identified as intermediate type, the nerve impulses are both slowed down and reduced in strength, probably because of abnormalities in both myelin and axons. Type X Charcot-Marie-Tooth disease is created by mutations in genetics on the X chromosome, among the 2 sex chromosomes. CMT is an acquired neurological disease characterized by a gradually progressive deterioration of the muscle mass in the foot, lower arm, hand, and leg, and a mild loss of sensation in the toes, limbs, and fingers. The first sign of CMT is usually a high curved foot or stride disruptions. Other symptoms of the disorder may include foot-bone problems such as high arches and hammer toes, issues with hand function and equilibrium, periodic lower leg and forearm muscular tissue cramping, loss of some normal reflexes, occasional partial view and/or hearing loss, and, in some individuals, scoliosis. People with CMT disease usually start to experience symptoms in teenage years or early the adult years. Life span is usually normal.
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