Chlorthalidone

Summarized by Plex Health
Last Updated: 02 May 2022
bilateral, simultaneous, acute angle closure glaucoma in pseudophakia induced by chlorthalidone. "bilateral, simultaneous, acute angle closure glaucoma in pseudophakia induced by chlorthalidone.", by Durai I, Mohan Dhavalikar M, Anand CP, Ganesh V, Krishnadas R. fig5: Right eye (Patient 2) B-scan ultrasosonography shows normal features suggesting resolution of choroidal detachment following withdrawal of chlorthalidone....

Chlorthalidone is a thiazide diuretic that aids prevent your body from absorbing way too much salt, which can cause liquid retention. It is 2-Chloro-5 benzenesulfonamide with the following structural formula: Chlorthalidone, USP is virtually insoluble in water, in ether, and in chloroform; soluble in methanol; somewhat soluble in ethanol. Chlorthalidone tablets are readily available having either 25 mg or 50 mg of chlorthalidone, USP and the following inactive ingredients: colloidal silicon dioxide, microcrystalline cellulose, pregelatinized starch, salt starch glycolate, stearic acid.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
2732C14H11ClN2O4S338.8C1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)OC1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)OInChI=1S/C14H11ClN2O4S/c15-11-6-5-8(7-12(11)22(16,20)21)14(19)10-4-2-1-3-9(10)13(18)17-14/h1-7,19H,(H,17,18)(H2,16,20,21)JIVPVXMEBJLZRO-UHFFFAOYSA-N2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide0.9338.0128057338.012805711856403522201010001
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