Cisplatin

Summarized by Plex Health
Last Updated: 09 May 2022
cisplatin "cisplatin", by Larry Ostby (Photographer). Cisplatin crystals, which is a platinum compound, and used as a chemotherapy drug....

Cisplatin is used together with other cancer drugs to deal with bladder cancer, testicular cancer, or ovarian cancer. Cisplatin might also be used for purposes not listed in this medication overview. A child treated with cisplatin might require a hearing test before receiving the first dosage. Utilizing cisplatin might increase your risk of developing leukemia. Cisplatin can hurt unborn infant if the mom or the daddy is using cisplatin. How commonly and the amount of times you get cisplatin will depend on the type of cancer you have. Your cancer treatments might be postponed based on the results. The physician will suggest medicine to keep you from feeling sick and tossing up after you get cisplatin. If you have pain or redness at the IV site, tell the nurse right away. Blood will be drawn frequently to inspect the following: kidney function; liver function; blood counts; blood levels of magnesium, potassium, phosphorus, salt, and calcium; You will obtain IV liquids before and after you obtain cisplatin. If your urine outcome decreases after you get cisplatin, tell the doctor. The supplements might be added to your IV fluid if you are obtaining IV fluid. Each 50 mL, 100 mL or 200 mL brownish-yellow vial of Cisplatin Injection contains: 1 mg/mL cisplatin, 9 mg/mL salt chloride, hydrochloric acid and/or sodium hydroxide to readjust pH, and water for injection to a final volume of 50 mL, 100 mL or 200 mL, specifically. The pH range of Cisplatin Injection is 3. 8 to 5. 9 Cisplatin Injection need to be further diluted before administration. Cisplatin is a hefty metal facility containing a central atom of platinum bordered by 2 chloride atoms and two ammonia molecules in the cis placement. It is soluble in water or saline at 1 mg/mL and in dimethylformamide at 24 mg/mL.

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Research Papers' Summaries

PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
5702198Cl2H6N2Pt300.05N.N.Cl[Pt]ClN.N.Cl[Pt]ClInChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2LXZZYRPGZAFOLE-UHFFFAOYSA-Lazane;dichloroplatinum298.955598298.955598220220500000003
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