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Congenital Heart Defects

Summarized by Plex Health
Last Updated: 02 May 2022
mice carrying a hypomorphic evi1 allele are embryonic viable but exhibit severe congenital heart defects. "mice carrying a hypomorphic evi1 allele are embryonic viable but exhibit severe congenital heart defects.", by Bard-Chapeau EA, Szumska D, Jacob B, Chua BQ, Chatterjee GC, Zhang Y, Ward JM, Urun F, Kinameri E, Vincent SD, Ahmed S, Bhattacharya S, Osato M, Perkins AS, Moore AW, Jenkins NA, Copeland NG. pone-0089397-g005: Cardiac malformations and failure in Evi1δex3/δex3 mice.(A) Transverse sections and (B) 3D reconstruction (left-ventral oblique view) of hearts from Evi1δex3/δex3 or wild type littermate (+/+) E15.5 embryos analyzed by magnetic resonance imaging (MRI). The...

A congenital heart problem is an issue with the structure of the heart. Congenital heart defects are one of the most common type of birth issue. The defects can include the walls of the heart, the shutoffs of the heart, and the arteries and veins near the heart. The blood flow can reduce down, go in the incorrect direction or to the incorrect place, or be obstructed totally. Physicians use a physical exam and special heart tests to identify congenital heart defects. Symptoms and signs of serious defects in babies consist of: Rapid breathing; Cyanosis, a blue tint to the skin, lips, and finger nails; Fatigue; Poor blood flow. Many congenital heart defects cause few or no signs and symptoms. Many children with congenital heart defects do not need treatment, however others do. As healthcare and therapy have advanced, children with a CHD are living longer and healthier lives. Some CHDs may be diagnosed throughout pregnancy making use of a special type of ultrasound called a fetal echocardiogram, which produces ultrasound images of the heart of the developing child. In some cases the heart problem can't be completely fixed, but these procedures can enhance blood flow and the way the heart works. It is essential to keep in mind that even if their heart defect has been fixed, many people with CHDs are not treated. Doctors often do not know why congenital heart defects occur, however a number of elements can raise the risk of having a baby born with a heart issue. Congenital heart defects can usually be found by a medical professional based on symptoms or by prenatal or newborn testings.

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