Congenital syphilis is a chronic infectious disease brought on by a spirochete acquired by the fetus in the womb prior to birth. Congenital syphilis is passed on to the child from the mother that acquired the disease before or while pregnant. Pregnant women with syphilis might have a reduction in estrogen while product progesterone degrees might increase. Symptoms of early congenital syphilis usually appear at three to fourteen weeks old yet may look like late as age 5 years. A pregnant mommy that has syphilis can spread out the infection via the placenta to the expected infant. Congenital syphilis is brought on by the germs Treponema pallidum, which is passed from mommy to child throughout fetal growth or at birth. As much as half of all babies infected with syphilis while they remain in the womb die quickly prior to or after birth. Regardless of the fact that this disease can be healed with prescription antibiotics if caught early, climbing rates of syphilis amongst pregnant women in the United States have increased the variety of babies born with congenital syphilis since 2013. Some babies with early congenital syphilis are asymptomatic at birth. Clinical manifestations of early congenital syphilis may consist of rhinitis, hepatosplenomegaly, skin breakout with desquamation, chorioretinitis and pigmentary chorioretinopathy, glaucoma, cataracts, interstitial keratitis, optic neuritis, periostitis and cortical demineralization of metaphysis and diaphysis areas of long bones, anaemia and thrombocytopenia. Infants may be born without medical signs of syphilis yet take place to develop late-stage symptoms of untreated congenital syphilis that consist of developing delay, neurologic manifestations and late congenital syphilis physical signs. Use darkfield microscopy or fluorescent antibody discovery to find Treponema pallidum in appropriate tissue samples.
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