Summarized by Plex Health
Last Updated: 04 May 2022

Cryoglobulins are antibodies that come to be gel-like or strong at low temperatures in the laboratory. In the lab, cryoglobulins appear of service in blood when the blood sample is cooled below 98. 6 F. Cryoglobulins come in three primary types, however in 90% of cases, the cause is hepatitis C. The disease in which cryoglobulins are found is called cryoglobulinemia. Cryoglobulins can cause inflammation in capillary, called vasculitis. The blood specimen need to be accumulated in a special way. Blood should NOT be attracted from a catheter that has heparin in it. The healthcare provider wraps a flexible band around the upper arm to apply pressure to the area and make the capillary swell with blood. The blood accumulates into an airtight vial or tube connected to the needle. You may wish to call ahead to ask to have your blood attracted by a lab technician that has experience gathering blood for this test.

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