Cytarabine

Summarized by Plex Health
Last Updated: 02 May 2022
inhibition of mtor-dependent autophagy sensitizes leukemic cells to cytarabine-induced apoptotic death. "inhibition of mtor-dependent autophagy sensitizes leukemic cells to cytarabine-induced apoptotic death.", by Bosnjak M, Ristic B, Arsikin K, Mircic A, Suzin-Zivkovic V, Perovic V, Bogdanovic A, Paunovic V, Markovic I, Bumbasirevic V, Trajkovic V, Harhaji-Trajkovic L. pone-0094374-g002: Cytarabine induces autophagy in REH cells.REH cells were incubated with cytarabine alone (3.2 μM) (A-C, E), or with cytarabine in the absence or presence of proteolysis inhibitors bafilomycin A1 (Baf; 10 nM) or chloroquine...

Cytarabine is used together with other cancer drugs to treat particular types of leukemia. Cytarabine is used to avoid or deal with leukemia related to meningitis. Cytarabine may also be used for purposes not detailed in this medicine guide. Cytarabine can increase your risk of blood loss or infection. Cytarabine can cause major side effects on your brain or central nervous system that might not be relatively easy to fix. If you have really feel confused or have any unusual thoughts or habits, tell your medical professional. Cytarabine may harm a coming child. Use efficient contraception to avoid pregnancy, and inform your doctor if you come to be pregnant. Cytarabine is additionally being examined in the treatment of other types of cancer. Cytarabine is additionally offered in a various form, integrated with Daunorubicin Hydrochloride. Interpretation from the NCI Drug Dictionary, Detailed scientific meaning and other names for this drug. If they can assist treat or stop problems other than the ones they are approved for, drugs are often studied to discover out. This patient information sheet uses only to accepted uses the medicine. Find Clinical Trials for Cytarabine, Check for tests from NCI's checklist of cancer medical tests now approving patients. If you have nausea or vomiting and vomiting after cytarabine, the physician may recommend medication to keep you from feeling sick and vomitting. Cytarabine might make your mouth sore and aggravated. The physician or nurse might give you oral rinses to keep your mouth clean after you obtain cytarabine. Inform the medical professional if you have abnormal kidney or liver function before you obtain cytarabine. Cytarabine might influence the way other medications work.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
6253C9H13N3O5243.22C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)OC1=CN(C(=O)N=C1N)[[email protected]]2[[email protected]]([[email protected]@H]([[email protected]](O2)CO)O)OInChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1UHDGCWIWMRVCDJ-CCXZUQQUSA-N4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one-2.1243.08552052243.0855205212938304521704400001
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