Desmopressin

Summarized by Plex Health
Last Updated: 02 May 2022
the novel desmopressin analogue [v4q5]ddavp inhibits angiogenesis, tumour growth and metastases in vasopressin type 2 receptor-expressing breast cancer models. "the novel desmopressin analogue [v4q5]ddavp inhibits angiogenesis, tumour growth and metastases in vasopressin type 2 receptor-expressing breast cancer models.", by Garona J, Pifano M, Orlando UD, Pastrian MB, Iannucci NB, Ortega HH, Podesta EJ, Gomez DE, Ripoll GV, Alonso DF. f1-ijo-46-06-2335: Peptide sequence of [V4Q5]dDAVP and immunofluorescence detection of vasopressin type 2 receptor in breast cancer and microvascular endothelial cell lines. Schematic view of (A) parental compound dDAVP (1-deamino-8-D-arginine vasopressin) and (B) novel analogue [V4Q5]dDAVP...

Desmopressin is used to help manage hemorrhaging disorders. You require to press the bottle or pump up until some of the medication sprays out if you are using the nasal spray for the first time. If you have not used the medicine for 5 days or longer, always prime the spray. Before using the medicine, delicately blow your nose to get rid of the nostrils. After using this medicine, wipe the suggestion of the container with a clean tissue then replace the cap. On the days that you use this medicine, only drink adequate liquids to quench thirst. For travelers, desmopressin is great for 3 weeks at area temperature. Your doctor may execute blood tests to see to it you do not have problems that would stop you from safely utilizing desmopressin. Fluid limitation is particularly important in children and older adults making use of desmopressin. Wait at least 12 hrs after your last nasal dosage prior to you take your first tablet if you were switched over from desmopressin nasal spray to desmopressin tablets. Your blood pressure will require to be examined frequently and you might need frequent blood tests. Take the medication as quickly as you can, yet skip the missed dose if it is virtually time for your next dosage. This is a problem that causes the body to lose way too much liquid and end up being dehydrated. It is additionally used to regulate bedwetting, and the regular urination and increased thirst brought on by particular types of brain injury or brain surgical treatment. Desmopressin is similar to a hormone that is created in the body. It acts on the kidneys to minimize the flow of urine. This medication is offered only with your doctor's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
5311065C46H64N14O12S21069.2C1CC(N(C1)C(=O)C2CSSCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)NC1C[[email protected]](N(C1)C(=O)[[email protected]@H]2CSSCCC(=O)N[[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)N[[email protected]](CCCN=C(N)N)C(=O)NCC(=O)NInChI=1S/C46H64N14O12S2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52)/t28-,29+,30+,31+,32+,33+,34+/m1/s1NFLWUMRGJYTJIN-PNIOQBSNSA-N(2S)-N-[(2R)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide-41068.426955881068.42695588489204001315197407700001
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