Dinoprostone
Summarized by Plex Health
Last Updated: 02 May 2022
CERVIDIL vaginal insert has dinoprostone, a prostaglandin analog. Each vaginal insert has 10 mg of dinoprostone in 241 mg of a cross-linked polyethylene oxide/urethane polymer that is semi-opaque, off-white colored, flat, rectangular fit with rounded corners and gauging 29 mm by 9. 5 mm by 0. 8 mm. The weaved polyester retrieval system has a lengthy tape-like end that is created to aid access of CERVIDIL at the end of the dosing period or earlier if scientifically suggested. It has a melting factor within the range of 65 to 69 C. Dinoprostone is soluble in ethanol and in 25% ethanol in water.
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Sources:
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f3bc9031-0620-4a50-b440-f661cadfe...
Research Papers' Summaries
PubChem - CovalentUnitCount
(Table source)| CID | MolecularFormula | MolecularWeight | CanonicalSMILES | IsomericSMILES | InChI | InChIKey | IUPACName | XLogP | ExactMass | MonoisotopicMass | TPSA | Complexity | Charge | HBondDonorCount | HBondAcceptorCount | RotatableBondCount | HeavyAtomCount | IsotopeAtomCount | AtomStereoCount | DefinedAtomStereoCount | UndefinedAtomStereoCount | BondStereoCount | DefinedBondStereoCount | UndefinedBondStereoCount | CovalentUnitCount |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5280360 | C20H32O5 | 352.5 | CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O | CCCCC[[email protected]@H](/C=C/[[email protected]]1[[email protected]@H](CC(=O)[[email protected]@H]1C/C=C\CCCC(=O)O)O)O | InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | XEYBRNLFEZDVAW-ARSRFYASSA-N | (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid | 2.8 | 352.22497412 | 352.22497412 | 94.8 | 469 | 0 | 3 | 5 | 12 | 25 | 0 | 4 | 4 | 0 | 2 | 2 | 0 | 1 |
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