Dronedarone
Summarized by Plex Health
Last Updated: 02 May 2022
"marked prolongation of qrs duration after initiation of dronedarone therapy.", by Genz C, Esperer HD, Schmeisser A, Braun-Dullaeus RC, Said SM. fig_2: Left bundle branch block pattern after two doses of dronedarone....
Dronedarone is a heart rhythm medication that aids lower your risk of requiring to be hospitalized for a heart rhythm disorder called atrial fibrillation. Dronedarone comes from the group of medications known as antiarrhythmics. It works straight on the heart tissue and will slow the nerve impulses in the heart. This helps keep the heart rhythm normal. This medication is readily available only with your medical professional's prescription.
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Sources:
https://www.drugs.com/mtm/dronedarone.html
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7fa41601-7fb5-4155-8e50-2ae903f0d...
https://www.mayoclinic.org/drugs-supplements/dronedarone-oral-route/description/drg-200731...
PubChem - CovalentUnitCount
(Table source)| CID | MolecularFormula | MolecularWeight | CanonicalSMILES | IsomericSMILES | InChI | InChIKey | IUPACName | XLogP | ExactMass | MonoisotopicMass | TPSA | Complexity | Charge | HBondDonorCount | HBondAcceptorCount | RotatableBondCount | HeavyAtomCount | IsotopeAtomCount | AtomStereoCount | DefinedAtomStereoCount | UndefinedAtomStereoCount | BondStereoCount | DefinedBondStereoCount | UndefinedBondStereoCount | CovalentUnitCount |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 208898 | C31H44N2O5S | 556.8 | CCCCC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C)C(=O)C3=CC=C(C=C3)OCCCN(CCCC)CCCC | CCCCC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C)C(=O)C3=CC=C(C=C3)OCCCN(CCCC)CCCC | InChI=1S/C31H44N2O5S/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3/h13-18,23,32H,5-12,19-22H2,1-4H3 | ZQTNQVWKHCQYLQ-UHFFFAOYSA-N | N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide | 7.2 | 556.29709368 | 556.29709368 | 97.2 | 800 | 0 | 1 | 7 | 18 | 39 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
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