Elbasvir and grazoprevir

Summarized by Plex Health
Last Updated: 02 May 2022

Elbasvir and grazoprevir are antiviral medications that avoid hepatitis C from multiplying in your body. Elbasvir and grazoprevir is a combination medicine used to treat chronic liver disease C in adults. elbasvir and grazoprevir is in some cases given together with another medicine called ribavirin. Elbasvir and grazoprevir is in some cases used in people who additionally have HIV. Utilizing elbasvir and grazoprevir can cause this virus to come to be active or get worse if you've ever had liver disease B. When taking elbasvir and grazoprevir with ribavirin: To ensure all medications are risk-free for you, inform your medical professional about all your clinical problems, and if you are pregnant or breastfeeding. Both men and women using ribavirin must use reliable birth control to stop pregnancy. You should not take ribavirin if you are pregnant, or if you are a man and your sex companion is pregnant. Keep making use of contraception for a minimum of 6 months after your last dose of ribavirin. If a pregnancy takes place while either the father or the mother is making use of ribavirin, tell your medical professional right away. If you've ever had hepatitis B, using elbasvir and grazoprevir can cause this virus to come to be active or worsen. Stopping all of a sudden might make your liver disease C more challenging to treat with antiviral medicine. Use all hepatitis C drugs as routed and check out all medicine guides you obtain. Everyone with chronic hepatitis C ought to stay under the care of a medical professional. Keep each tablet computer in the foil blister pack until you prepare to take it.

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

** If you believe that content on the Plex is summarised improperly, please, contact us, and we will get rid of it quickly; please, send an email with a brief explanation.

PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
91669168C87H105N15O16S1648.9CC(C)C(C(=O)N1CCCC1C2N=CC(=N2)C3=CC4=C(C=C3)C5=CC6=C(N5C(O4)C7=CC=CC=C7)C=CC(=C6)C8=CN=C(N8)C9CCCN9C(=O)C(C(C)C)NC(=O)OC)NC(=O)OC.CC(C)(C)C1C(=O)N2CC(CC2C(=O)NC3(CC3C=C)C(=O)NS(=O)(=O)C4CC4)OC5=NC6=C(C=CC(=C6)OC)N=C5CCCCCC7CC7OC(=O)N1CC(C)[[email protected]@H](C(=O)N1CCC[[email protected]@H]1C2N=CC(=N2)C3=CC4=C(C=C3)C5=CC6=C(N5[[email protected]@H](O4)C7=CC=CC=C7)C=CC(=C6)C8=CN=C(N8)[[email protected]@H]9CCCN9C(=O)[[email protected]](C(C)C)NC(=O)OC)NC(=O)OC.CC(C)(C)[[email protected]]1C(=O)N2C[[email protected]@H](C[[email protected]]2C(=O)N[[email protected]@]3(C[[email protected]]3C=C)C(=O)NS(=O)(=O)C4CC4)OC5=NC6=C(C=CC(=C6)OC)N=C5CCCCC[[email protected]@H]7C[[email protected]]7OC(=O)N1InChI=1S/C49H55N9O7.C38H50N6O9S/c1-27(2)41(54-48(61)63-5)45(59)56-20-10-14-37(56)43-50-25-34(52-43)30-17-19-36-32(22-30)23-39-33-18-16-31(24-40(33)65-47(58(36)39)29-12-8-7-9-13-29)35-26-51-44(53-35)38-15-11-21-57(38)46(60)42(28(3)4)55-49(62)64-6;1-6-22-19-38(22,35(47)43-54(49,50)25-13-14-25)42-32(45)29-18-24-20-44(29)34(46)31(37(2,3)4)41-36(48)53-30-16-21(30)10-8-7-9-11-27-33(52-24)40-28-17-23(51-5)12-15-26(28)39-27/h7-9,12-13,16-19,22-28,37-38,41-42,44,47H,10-11,14-15,20-21H2,1-6H3,(H,50,52)(H,54,61)(H,55,62);6,12,15,17,21-22,24-25,29-31H,1,7-11,13-14,16,18-20H2,2-5H3,(H,41,48)(H,42,45)(H,43,47)/t37-,38+,41-,42-,44?,47-;21-,22-,24-,29+,30-,31-,38-/m01/s1SVPWXLXHFSKQRN-QZUDGTEMSA-N(1R,18R,20R,24S,27S)-24-tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-7-methoxy-22,25-dioxo-2,21-dioxa-4,11,23,26-tetrazapentacyclo[24.2.1.03,12.05,10.018,20]nonacosa-3,5(10),6,8,11-pentaene-27-carboxamide;methyl N-[(2S)-1-[(2R)-2-[4-[(6S)-10-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazin-3-yl]-2H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate1647.758443491647.7584434938833700621211190131210002
*** If you want us to remove all links leading to your domain from Plex.page and never use your website as a source of the "Online Knowledge", please contact us using a corporate email and we will remove everything in 10 business days.

logo

Plex Page is a Biology & Health Sciences "Online Knowledge Base," where a machine summarizes all the summaries.