Entecavir

Summarized by Plex Health
Last Updated: 02 May 2022
a granulomatous drug eruption induced by entecavir. "a granulomatous drug eruption induced by entecavir.", by Yoon J, Park D, Kim C. F1: (A) The patient presented with multiple pruritic erythematous papules on the forehead, both periorbital areas and cheeks 2 months after initiating entecavir therapy. (B) Closed view. (C) Resolved state after discontinuation of the entecavir....

Entecavir is an antiviral medication that is used to deal with chronic hepatitis B virus in children and adults who are at least 2 years old and evaluate at least 22 pounds. Hepatitis B might become active or get even worse after you stop utilizing entecavir. Taking medicine to treat chronic hepatitis B can cause HIV infection to come to be immune to particular HIV and AIDS medicines. Inform your medical professional about all medicines you have used to treat liver disease B in the past. If you have used specific other medicines for HBV, Entecavir might not be the right drug. Measure liquid medication carefully, utilizing the application syringe with your medicine. The chemical name for entecavir is 2-amino-1,9-dihydro-9 [4hydroxy-32methylenecyclopentyl] -6 H-purin-6one, monohydrate. Entecavir has the following structural formula: Entecavir USP is a white to off-white powder. It is slightly soluble in water, and the pH of the saturated remedy in water is 7. 9 at 25 C 0. 5 C. Entecavir film-coated tablets are readily available for oral administration in toughness of 0. 5 mg and 1 mg of entecavir USP. Entecavir 0. 5 mg and 1 mg film-coated tablets contain the adhering to inactive components: crospovidone, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, and titanium dioxide. Meets USP Dissolution Test 2. It belongs to the family of medicines called antivirals. Antivirals are used to treat infections that are caused by viruses. This medication will not cure the liver disease B virus, but it will keep it from reproducing and causing more liver damage. This medicine is available only with your physician's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
135398508C12H15N5O3277.28C=C1C(CC(C1CO)O)N2C=NC3=C2N=C(NC3=O)NC=C1[[email protected]](C[[email protected]@H]([[email protected]]1CO)O)N2C=NC3=C2N=C(NC3=O)NInChI=1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8-/m0/s1QDGZDCVAUDNJFG-FXQIFTODSA-N2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one-1.3277.11748936277.1174893612648004522003300001
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