Summarized by Plex Health
Last Updated: 04 May 2022
investigation of genetic disturbances in oxygen sensing and erythropoietin signaling pathways in cases of idiopathic erythrocytosis. "investigation of genetic disturbances in oxygen sensing and erythropoietin signaling pathways in cases of idiopathic erythrocytosis.", by Dinardo CL, Santos PC, Schettert IT, Soares RA, Krieger JE, Pereira AC. fig1: Representation of diagnostic strategy for patients with erythrocytosis without acquired secondary causes. The most common example of primary erythrocytosis is polycythemia vera (PV). Notably, the majority of idiopathic erythrocytosis patients cannot be classified into...

Erythrocytosis is when you have more red blood cells than normal. Red blood cells are also called erythrocytes. Red cell carry oxygen throughout your body and remove carbon dioxide from your body. Your bone marrow makes red blood cells and releases them into your blood stream. Red blood cells live for about 120 days and after that die. This type of erythrocytosis additionally happens when your body produces way too many blood cells, but it is not brought on by a trouble with your bone marrow. If you only have way too many red blood cells without having way too many white blood cells or platelets, and you don't have secondary erythrocytosis, this may be why. Primary erythrocytosis can also be triggered by a type of blood cancer called polycythemia vera. Polycythemia vera can be lethal because the extra red blood cells can cause your blood to slow down and enlarge down if it isn't treated. Secondary erythrocytosis can have many causes. Your red cell bring oxygen to your body. If your oxygen is low for any reason, your body might increase its production of red blood cells to give you more oxygen. The hormone EPO that regulates the production of red cell is made in your kidneys. Anabolic steroids and other performance-enhancing drugs can cause your body to increase the variety of red blood cells it generates. Sometimes, you don't have a lot of red cell, however your red blood cells are too concentrated because you don't have enough fluid in your blood stream.

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