Estradiol

Summarized by Plex Health
Last Updated: 05 May 2022
17beta-estradiol counteracts neuropathic pain: a behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice. "17beta-estradiol counteracts neuropathic pain: a behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice.", by Vacca V, Marinelli S, Pieroni L, Urbani A, Luvisetto S, Pavone F. f8: Sex-dependent differences in the expression/activation of spinal astrocytes and spinal microglia at CCI D121.(A,B) Representative examples of high magnification (63X) IF images of GFAP (astrocytes; green), p-p38 (phosphorylated-p38; red), and their colocalization (merge, yellow)...

Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body. Estradiol is used to treat menopause symptoms such as vaginal changes and hot flashes, and to avoid weakening of bones in menopausal women. Estradiol is additionally used to deal with low estrogen levels in women with ovarian failure. It is indicated to treat specific types of breast cancer and prostate cancer. Estradiol might additionally be used for objectives not detailed in this medicine guide. You need to not use estradiol if you have: undiagnosed vaginal bleeding, liver disease, a bleeding disorder, or if you have ever before had a cardiac arrest, a stroke, an embolism, or cancer of the breast, uterus/cervix, or vaginal area. Estradiol might increase your risk of developing uterine cancer. Do not use estradiol if you are pregnant. Tell your medical professional right away if you conceive throughout therapy. Estradiol needs to not be used to stop heart dementia, disease, or stroke, because this medication may in fact increase your risk of developing these problems. Utilizing estradiol may increase your risk of cancer of the breast, womb, or ovaries. Estradiol decreases the hormone needed to generate breast milk and can slow breast milk production. Estradiol might increase your risk of developing uterine cancer. To assist lower this risk, your medical professional may desire you to take a progestin. Report any unusual vaginal bleeding to your doctor immediately. If you are making use of estradiol spray, prevent fire, flame, or cigarette smoking till the spray has dried out. Do not use lotion or sunscreen over the area for at least one hour.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
5757C18H24O2272.4CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC[[email protected]]12CC[[email protected]]3[[email protected]]([[email protected]@H]1CC[[email protected]@H]2O)CCC4=C3C=CC(=C4)OInChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1VOXZDWNPVJITMN-ZBRFXRBCSA-N(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol4272.177630004272.17763000440.538202202005500001
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