Etravirine

Summarized by Plex Health
Last Updated: 02 May 2022

Etravirine is a tablet that consists of medication used to deal with infection caused by the human immunodeficiency virus. Etravirine comes from a group of medications called nonnucleoside reverse transcriptase preventions. Etravirine can decrease how soon you will see symptoms of HIV or slow down the damages created by HIV, however it can not heal HIV infection. Etravirine needs to be taken with food. Etravirine may be liquified in a small amount of water to ensure that the patient might drink the medication rather of ingesting the tablets whole. Some side effects, such as low blood matters, can be found with blood tests, So it is very essential that you pertain to clinic at on a regular basis intended times and have blood tests done. Etravirine can also impact blood levels of specific other drugs. If the virus is not regulated throughout maternity, hiv can be passed to your baby. Women with HIV or AIDS ought to not breast-feed an infant. Even if your child is birthed without HIV, the virus may be passed to the child in your breast milk. Your child's dosage needs may change if the child gains or reduces weight. The chemical name for etravirine is 4- [6-amino-5bromo-2 [amino] -4 pyrimidinyl] oxy] -3,5-dimethylbenzonitrile. Its molecular formula is C20H15BrN6O and its molecular weight is 435. 28 g/mol. Etravirine has the adhering to structural formula: Etravirine is a white to a little yellowish-brown powder. Etravirine is practically insoluble in water and easily soluble in some organic solvents like N,N-dimethylformamide and tetrahydrofuran. Etravirine tablets are for oral administration. Each etravirine tablet contains 25 mg, 100 mg or 200 mg of etravirine. It additionally includes the inactive ingredients: croscarmellose salt, crospovidone, colloidal silicon dioxide, hypromellose, low-substituted hydroxy propyl cellulose, magnesium stearate and microcrystalline cellulose.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
193962C20H15BrN6O435.3CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#NCC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#NInChI=1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27)PYGWGZALEOIKDF-UHFFFAOYSA-N4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile4.5434.04907434.0490712160902742800000001
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