Fingolimod

Summarized by Plex Health
Last Updated: 02 May 2022
fingolimod phosphate attenuates oligomeric amyloid β-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons. "fingolimod phosphate attenuates oligomeric amyloid β-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons.", by Doi Y, Takeuchi H, Horiuchi H, Hanyu T, Kawanokuchi J, Jin S, Parajuli B, Sonobe Y, Mizuno T, Suzumura A. pone-0061988-g004: Neuroprotective effects of FTY720-P depended on BDNF.(A) Fluorescent microscopic images of mouse primary cortical neuron cultures. The BDNF scavenger canceled the neuroprotective effects of FTY720-P. Neurons were stained with anti–MAP-2 antibodies (green) and Aβ...

Fingolimod is used to deal with falling back several sclerosis in children and adults who are at least 10 years old. You should not use fingolimod if you take particular heart rhythm medications, or if you've had a major heart condition in the past 6 months. Severe heart conditions consist of specific heart rhythm disorders, heart failure, chest pain, cardiovascular disease, or stroke. Your physician will inspect your heart function prior to you start taking fingolimod. Making use of fingolimod might increase your risk of developing skin cancer. Your MS symptoms might return when you stop taking fingolimod. It has a molecular weight of 343. 93 g/mol. Fingolimod is provided as 0. 5 mg difficult gelatin pills for oral use. Each fingolimod 0. 5 mg pill consists of the following non-active ingredients: jelly, magnesium stearate, microcrystalline cellulose, titanium dioxide and iron oxide yellow. The imprinting ink consists of shellac, black iron oxide and trace amount of Potassium salts of potassium hydroxides. This medicine will not heal MS, however it might slow some debilitating effects and decrease the number of relapses of the disease. This medication is offered only with your physician's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
107970C19H33NO2307.5CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)NCCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)NInChI=1S/C19H33NO2/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22/h9-12,21-22H,2-8,13-16,20H2,1H3KKGQTZUTZRNORY-UHFFFAOYSA-N2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol4.2307.251129295307.25112929566.5258033122200000001
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