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Fluoxetine

Summarized by Plex Health
Last Updated: 01 May 2022
fluoxetine modulates breast cancer metastasis to the brain in a murine model. "fluoxetine modulates breast cancer metastasis to the brain in a murine model.", by Shapovalov Y, Zettel M, Spielman SC, Amico-Ruvio SA, Kelly EA, Sipe GO, Dickerson IM, Majewska AK, Brown EB. Fig4: The effects of fluoxetine treatment on dendriticspine turnover and PNNs. A-C: Dendritic spine turnover wasmeasured in adult mouse visual cortex in vivo, by imaging corticaldendrites four days apart using 2-photon microscopy. A) Representative images...

Fluoxetine is a selective serotonin reuptake inhibitor antidepressant. Fluoxetine is occasionally used along with another medicine called olanzapine to deal with manic clinical depression created by bipolar affective disorder. If you have used an MAO prevention in the past 14 days, do not use fluoxetine. You have to wait 5 weeks after quiting fluoxetine before you can take thioridazine or an MAOI. Some youths have thoughts about self-destruction when first taking an antidepressant. Ask your physician about taking fluoxetine if you are pregnant. Taking an SSRI antidepressant during late maternity may cause significant clinical problems in the baby. Fluoxetine aids lots of people recover from depression, and it has less side effects than a few other antidepressants. Fluoxetine is available only on prescription. It could be best to stop driving, cycling or using equipment for the first couple of days of treatment until you know just how this medicine makes you really feel. Fluoxetine will not change your personality, it will simply help you feel like on your own again. It is additionally marketed for the therapy of premenstrual dysphoric disorder. It is assigned -Nmethyl-3phenyl-3 [oxy] propylamine hydrochloride and has the empirical formula of C17H18F3NOHCl. Its molecular weight is 345. 79. The structural formula is: Fluoxetine hydrochloride is a white to beige crystalline solid with a solubility of 14 mg/mL in water. The pills also have lactose monohydrate, microcrystalline cellulose, colloidal silicone dioxide, gelatin, titanium dioxide, FD & C Blue No. 1 and FD & C Red No.

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Research Papers' Summaries

PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
3386C17H18F3NO309.33CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)FCNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)FInChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3RTHCYVBBDHJXIQ-UHFFFAOYSA-NN-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine4309.13404868309.1340486821.330801562201010001
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