Fostamatinib

"effects of cyp3a4 inhibitors ketoconazole and verapamil and the cyp3a4 inducer rifampicin on the pharmacokinetic parameters of fostamatinib: results from in vitro and phase i clinical studies.", by Martin P, Gillen M, Millson D, Oliver S, Brealey C, Grossbard EB, Baluom M, Lau D, Sweeny D, Mant T, Craven K. Fig1: Determination of the CYP450 isoforms involved in R406 metabolism by using specific chemical inhibitors and expressed enzymes...

Fostamatinib is used to deal with chronic immune thrombocytopenia, a bleeding problem triggered by a lack of platelets in the blood. Fostamatinib might be used for purposes not provided in this medication overview. Fostamatinib can raise your high blood pressure, often to unsafe levels. Fostamatinib might cause liver problems, extreme diarrhea, and infections. Use reliable birth control to avoid maternity while you are utilizing fostamatinib and for at least 1 month after your last dosage. Follow all instructions on your prescription label and review all medication guides or direction sheets. Your doctor might sometimes change your dosage. Use the medication precisely as directed. You might take fostamatinib with or without food. Fostamatinib can cause diarrhea. Fostamatinib can elevate your high blood pressure, in some cases to hazardous degrees. Your blood pressure will need to be inspected often. Your medical professional might change your dose, or you might need to stop utilizing fostamatinib based on test outcomes. Avoid the missed dose and use your next dose at the regular time.

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