Summarized by Plex Health
Last Updated: 02 May 2022

GM2-gangliosidosis, AB variant is a rare acquired disorder that gradually destroys nerve cells in the brain and spinal cord. Signs and symptoms of the AB variant come to be noticeable in early stage. As the disease proceeds, children with the AB variant experience seizures, vision and hearing loss, intellectual disability, and paralysis. An eye irregularity called a cherry-red area, which can be related to an eye examination, is characteristic of this disorder. Children with the AB variant usually live only into early youth.

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