Gemfibrozil

Summarized by Plex Health
Last Updated: 02 May 2022
activation of sterol regulatory element binding factors by fenofibrate and gemfibrozil stimulates myelination in zebrafish. "activation of sterol regulatory element binding factors by fenofibrate and gemfibrozil stimulates myelination in zebrafish.", by Ashikawa Y, Nishimura Y, Okabe S, Sasagawa S, Murakami S, Yuge M, Kawaguchi K, Kawase R, Tanaka T. F5: Fenofibrate and gemfibrozil increase mbp promoter-driven fluorescent reporter expression through activation of SREBFs.(A) Representative images from in vivo analysis of Tg (mbp: mCitrine, eno2: Cerulean) zebrafish incubated with or without the indicated concentrations of...

The chemical name is 5-2,2-dimethylpentanoic acid, with the adhering to structural formula: C15H22O3 M. W 250. 33 Gemfibrozil is a white strong which is stable under average problems. The solubility in water and acid is 0. 0019% and in thin down base it is higher than 1%. The melting point is 58 -61 C. Each tablet computer for oral administration consists of 600 mg of gemfibrozil. Furthermore, each tablet consists of the following non-active components: calcium stearate, colloidal silicon dioxide, croscarmellose salt, FD&C red # 40 aluminum lake, FD&C yellow # 6 light weight aluminum lake, hydroxypropyl cellulose, hypromellose, microcrystalline cellulose, polyethylene glycol, polysorbate 80, pregelatinized starch, and titanium dioxide. Gemfibrozil is additionally used to lower the risk of stroke, heart attack, or other heart complications in specific people with high cholesterol and triglycerides that have not been helped by other treatment methods. This may aid stop the growth of pancreatitis brought on by high levels of triglycerides in the blood. Gemfibrozil might also be used to stop specific types of heart troubles in patients with risk variables for heart troubles. This medication is readily available only with your medical professional's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
3463C15H22O3250.33CC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)OCC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)OInChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)HEMJJKBWTPKOJG-UHFFFAOYSA-N5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid3.8250.15689456250.1568945646.527301361800000001
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