Generalized pustular psoriasis is a serious form of a skin disorder called psoriasis. GPP and other forms of psoriasis are caused by abnormal inflammation. Inflammation is a normal immune system response to injury and foreign invaders. Individuals with GPP have duplicated episodes in which large areas of skin become red and irritated and develop small pus-filled sores. While many affected people have features only of GPP, some develop features of another skin problem called psoriasis vulgaris, either before or after GPP appears. PV, one of the most common type of psoriasis, is characterized by red, flaky patches of skin on components of the body.
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