Glecaprevir And Pibrentasvir

Summarized by Plex Health
Last Updated: 02 May 2022

Glecaprevir and pibrentasvir is a combination antiviral medicine used to deal with chronic liver disease C in people with HCV genotype 1, 2, 3, 4, 5, or 6. Glecaprevir and pibrentasvir may additionally be used for objectives not noted in this medicine overview. You should not use glecaprevir and pibrentasvir if you have severe liver disease, or if you also take atazanavir or rifampin. If you've ever before had hepatitis B, it might become active or become worse after you quit utilizing glecaprevir and pibrentasvir. Your physician will do blood tests to ensure you do not have conditions that would prevent you from securely utilizing glecaprevir and pibrentasvir. Quiting instantly can make your condition harder to treat with hepatitis C antiviral medicine. Use all hepatitis C drugs as directed and check out all medication guides you receive. Every individual with liver disease C must stay under the treatment of a doctor. If you've ever had liver disease B, this virus may end up being active or become worse in the months after you quit utilizing glecaprevir and pibrentasvir.

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

** If you believe that content on the Plex is summarised improperly, please, contact us, and we will get rid of it quickly; please, send an email with a brief explanation.

PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
85471918C95H111F9N16O17S1952.0CC(C(C(=O)N1CCCC1C2=NC3=C(N2)C=C(C(=C3)F)C4CCC(N4C5=CC(=C(C(=C5)F)N6CCC(CC6)C7=CC=C(C=C7)F)F)C8=CC9=C(C=C8F)N=C(N9)C1CCCN1C(=O)C(C(C)OC)NC(=O)OC)NC(=O)OC)OC.CC1(CC1)S(=O)(=O)NC(=O)C2(CC2C(F)F)NC(=O)C3CC4CN3C(=O)C(NC(=O)OC5CCCC5OCC=CC(C6=NC7=CC=CC=C7N=C6O4)(F)F)C(C)(C)CC[[email protected]]([[email protected]@H](C(=O)N1CCC[[email protected]]1C2=NC3=C(N2)C=C(C(=C3)F)[[email protected]]4CC[[email protected]@H](N4C5=CC(=C(C(=C5)F)N6CCC(CC6)C7=CC=C(C=C7)F)F)C8=CC9=C(C=C8F)N=C(N9)[[email protected]@H]1CCCN1C(=O)[[email protected]]([[email protected]@H](C)OC)NC(=O)OC)NC(=O)OC)OC.CC1(CC1)S(=O)(=O)NC(=O)[[email protected]]2(C[[email protected]]2C(F)F)NC(=O)[[email protected]@H]3C[[email protected]@H]4CN3C(=O)[[email protected]@H](NC(=O)O[[email protected]@H]5CCC[[email protected]]5OC/C=C/C(C6=NC7=CC=CC=C7N=C6O4)(F)F)C(C)(C)CInChI=1S/C57H65F5N10O8.C38H46F4N6O9S/c1-29(77-3)49(67-56(75)79-5)54(73)70-19-7-9-47(70)52-63-41-25-35(37(59)27-43(41)65-52)45-15-16-46(72(45)34-23-39(61)51(40(62)24-34)69-21-17-32(18-22-69)31-11-13-33(58)14-12-31)36-26-42-44(28-38(36)60)66-53(64-42)48-10-8-20-71(48)55(74)50(30(2)78-4)68-57(76)80-6;1-35(2,3)28-32(50)48-19-20(17-24(48)30(49)46-37(18-21(37)29(39)40)33(51)47-58(53,54)36(4)14-15-36)56-31-27(43-22-9-5-6-10-23(22)44-31)38(41,42)13-8-16-55-25-11-7-12-26(25)57-34(52)45-28/h11-14,23-30,32,45-50H,7-10,15-22H2,1-6H3,(H,63,65)(H,64,66)(H,67,75)(H,68,76);5-6,8-10,13,20-21,24-26,28-29H,7,11-12,14-19H2,1-4H3,(H,45,52)(H,46,49)(H,47,51)/b;13-8+/t29-,30-,45-,46-,47+,48+,49+,50+;20-,21+,24+,25-,26-,28-,37-/m11/s1ZVVGTYQPRVEJOH-GGZXVAPBSA-N(1R,14E,18R,22R,26S,29S)-26-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-[(1-methylcyclopropyl)sulfonylcarbamoyl]cyclopropyl]-13,13-difluoro-24,27-dioxo-2,17,23-trioxa-4,11,25,28-tetrazapentacyclo[26.2.1.03,12.05,10.018,22]hentriaconta-3,5,7,9,11,14-hexaene-29-carboxamide;methyl N-[(2S,3R)-1-[(2S)-2-[6-[(2R,5R)-1-[3,5-difluoro-4-[4-(4-fluorophenyl)piperidin-1-yl]phenyl]-5-[6-fluoro-2-[(2S)-1-[(2S,3R)-3-methoxy-2-(methoxycarbonylamino)butanoyl]pyrrolidin-2-yl]-3H-benzimidazol-5-yl]pyrrolidin-2-yl]-5-fluoro-1H-benzimidazol-2-yl]pyrrolidin-1-yl]-3-methoxy-1-oxobutan-2-yl]carbamate1951.79236561950.789010840337600732241380151501102
*** If you want us to remove all links leading to your domain from Plex.page and never use your website as a source of the "Online Knowledge", please contact us using a corporate email and we will remove everything in 10 business days.

logo

Plex Page is a Biology & Health Sciences "Online Knowledge Base," where a machine summarizes all the summaries.