Haemophilia

Summarized by Plex Health
Last Updated: 04 May 2022
epidemiology & social costs of haemophilia in india. "epidemiology & social costs of haemophilia in india.", by Kar A, Phadnis S, Dharmarajan S, Nakade J. F4: Observed (calculated at 0.9 per 1,00,000) and estimated (calculated at 4 per 1,00,000 population) prevalence of haemophilia A for states and UT of India. (Source: Authors’ calculation based on data from Ref. 15)....

Haemophilia is an inherited bleeding disorder where blood does not thicken effectively. Internal bleeding episodes or bleeds' are the major problem for lots of people with haemophilia. A change in the F8 gene, which makes blood clotting variable VIII, causes haemophilia A. Men that lug the hereditary change will pass it on their children but not their children. Women who carry the hereditary change may pass it on to their sons and daughters: There is a 50 per cent chance at each birth of a kid that the boy will have the hereditary change and therefore have haemophilia. Children with the genetic change may or may not have symptoms of haemophilia. Women with an altered F8 or F9 gene usually have another duplicate that is not changed. Normally, when you reduced yourself, substances in your blood called clotting factors blend with blood cells called platelets to make your blood sticky and form an embolism. People with haemophilia might have: nosebleeds that take a long period of time to stop; blood loss from injuries that lasts a very long time; hemorrhaging periodontals; skin that bruises conveniently; pain and tightness around joints, such as arm joints, since of hemorrhaging inside the body. Blood from the umbilical cable can be tested at birth if there's a family background of haemophilia.

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