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Haloperidol

Summarized by Plex Health
Last Updated: 02 May 2022
the role of abcb5 alleles in susceptibility to haloperidol-induced toxicity in mice and humans. "the role of abcb5 alleles in susceptibility to haloperidol-induced toxicity in mice and humans.", by Zheng M, Zhang H, Dill DL, Clark JD, Tu S, Yablonovitch AL, Tan MH, Zhang R, Rujescu D, Wu M, Tessarollo L, Vieira W, Gottesman MM, Deng S, Eberlin LS, Zare RN, Billard JM, Gillet JP, Li JB, Peltz G. pmed.1001782.g005: (A, B) Abcb5 knockout mice have a prolonged haloperidol-induced latency.In two independent experiments shown in (A) and (B), Abcb5 knockout mice and wild-type littermates (gender indicated by male or female) were treated with haloperidol...

Haloperidol is the first of the butyrophenone collection of significant antipsychotics. It is also used to regulate the symptoms of Tourette's disorder. This medicine ought to not be used to deal with actions problems in older adult patients that have dementia. Haloperidol is also used to deal with serious behavior problems or hyperactivity in children that have already been treated with psychotherapy or other medications that did not work well. This medicine is available only with your doctor's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
3559C21H23ClFNO2375.9C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)FC1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)FInChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2LNEPOXFFQSENCJ-UHFFFAOYSA-N4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one3.2375.1401348375.140134840.545101462600000001
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