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Hydralazine

Summarized by Plex Health
Last Updated: 02 May 2022
hydralazine target: from blood vessels to the epigenome. "hydralazine target: from blood vessels to the epigenome.", by Arce C, Segura-Pacheco B, Perez-Cardenas E, Taja-Chayeb L, Candelaria M, Dueñnas-Gonzalez A. F5: In in vitro methyltransferase assay of hydralazine. There was no digestion with HpaII (lanes H, with 0 and 5 μM of hydralazine) indicating full methylation. Starting at 10 μM of hydralazine, bands in the...

Hydralazine is a vasodilator that works by relaxing the muscular tissues in your capillary to assist them expand. Hydralazine is used to treat high blood pressure. Hydralazine may also be used for functions not provided in this drug guide. You ought to not use hydralazine if you have coronary artery disease, or rheumatic heart disease affecting the mitral valve. If you are pregnant or plan to come to be pregnant, tell your medical professional. Hydralazine can pass into breast milk, yet impacts on the nursing infant are not understood. High blood pressure typically has no symptoms. You might need to use high blood pressure medicine for the remainder of your life. Miss the missed out on dosage if it is almost time for your next set up dose. Take hydralazine with food, Food increases the amount of medication that enters your body. It is necessary to take this medication the same way and at the same time daily, so your blood pressure is regulated with the same amount of medication daily. If your blood pressure degree is low or high, your physician will inform you what to do. Your dose of hydralazine may change based on your blood pressure level. Hydralazine may affect the way some medications work. Its chemical name is 1-hydrazinophthalazine monohydrochloride, and its structural formula is: HydrALAZINE hydrochloride USP is a white to off-white, odor free crystalline powder. It is soluble in water, a little soluble in alcohol, and very a little soluble in ether. It melts at about 275 C, with decomposition. Each tablet for oral administration includes 25 mg, 50 mg or 100 mg HydrALAZINE hydrochloride USP. Tablets additionally contain mannitol, microcrystalline cellulose, salt starch glycolate, stearic acid and FD&C Yellow # 6.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
3637C8H8N4160.18C1=CC=C2C(=C1)C=NN=C2NNC1=CC=C2C(=C1)C=NN=C2NNInChI=1S/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)RPTUSVTUFVMDQK-UHFFFAOYSA-Nphthalazin-1-ylhydrazine0.7160.074896272160.07489627263.815002411200000001
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