Summarized by Plex Health
Last Updated: 02 May 2022
a translational continuum of model systems for evaluating treatment strategies in alzheimer's disease: isradipine as a candidate drug. "a translational continuum of model systems for evaluating treatment strategies in alzheimer's disease: isradipine as a candidate drug.", by Copenhaver PF, Anekonda TS, Musashe D, Robinson KM, Ramaker JM, Swanson TL, Wadsworth TL, Kretzschmar D, Woltjer RL, Quinn JF. f6-0040634: Chronic treatment with isradipine inhibits the accumulation of Aβ in 3×TgAD mice. (A) Body weights of wild-type control mice (wt) and 3×TgAD mice (Tg) that were treated with vehicle (V.) or isradipine (israd.). There...

Isradipine is a calcium villain offered for oral administration in pills containing 2. 5 mg or 5 mg. High blood pressure includes to the work of the heart and arteries. The heart and arteries might not function effectively if it continues for a long time. This can harm the blood vessels of the brain, heart, and kidneys, causing a stroke, heart failure, or kidney failure. High blood pressure might additionally increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled. Isradipine is a calcium network blocker. It works by affecting the movement of calcium into the cells of the heart and capillary. Because of this, isradipine kicks back capillary and increases the supply of blood and oxygen to the heart while minimizing its work. This medication is offered only with your doctor's prescription.

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PubChem - CovalentUnitCount

(Table source)
3784C19H21N3O5371.4CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OCCC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OCInChI=1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3HMJIYCCIJYRONP-UHFFFAOYSA-N3-O-methyl 5-O-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate4.3371.14812078371.1481207810468501862701010001
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