Ixazomib

Summarized by Plex Health
Last Updated: 03 May 2022

Ixazomib is used to treat several myeloma, in combination chemotherapy with lenalidomide and dexamethasone. Do not use ixazomib with lenalidomide if you are pregnant, or if you are a man and your sex-related partner is pregnant. If you are a woman taking dexamethasone: If you use contraceptive pill or other hormonal birth control, use an obstacle type of birth control such as a condom, diaphragm, cervical cap, or contraceptive sponge. Do not take your dexamethasone dose at the same time you take ixazomib. The chemical name of ixazomib citrate is 1,32-dioxaborolane-4,4-diacetic acid, 2- [1 [2- [amino] acetyl] amino] -3 methylbutyl] -5 oxo- and the structural formula is: The molecular formula for ixazomib citrate is C20H23BCl2N2O9 and its molecular weight is 517. 12. The solubility of ixazomib citrate in 0. 1 N HCl at 37 C is 0. 61 mg/mL. The 4 mg capsule covering includes red and yellow iron oxide, the 3 mg pill shell includes black iron oxide and the 2. 3 mg pill shell contains red iron oxide. It disrupts the growth of cancer cells, which are eventually damaged by the body. Ixazomib is an antineoplastic agent. This medicine is readily available only with your doctor's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
25183872C14H19BCl2N2O4361.0B(C(CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)OB([[email protected]](CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)OInChI=1S/C14H19BCl2N2O4/c1-8(2)5-12(15(22)23)19-13(20)7-18-14(21)10-6-9(16)3-4-11(10)17/h3-4,6,8,12,22-23H,5,7H2,1-2H3,(H,18,21)(H,19,20)/t12-/m0/s1MXAYKZJJDUDWDS-LBPRGKRZSA-N[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid360.0814926360.081492698.741204472301100001
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