Lapatinib is used to treat advanced hormone-related breast cancer that has advanced or spread after therapy with other cancer medications. Lapatinib is used for this condition only if your tumor tests positive for a protein called human skin growth variable receptor 2. Both women and men making use of lapatinib must use reliable birth control to stop pregnancy. Keep making use of contraception for at least 1 week after your last dosage. If a pregnancy takes place while either the mom or the dad is making use of lapatinib, inform your medical professional right away. When used with letrozole, the common dosage of lapatinib is 6 tablets taken daily everyday. It is present as the ditosylate salt, with chemical name N-6 [5-2furanyl] -4 quinazolinamine bis. Lapatinib ditosylate has the following chemical structure: Lapatinib is a yellow solid, and its solubility in water is 0. 007 mg/mL and in 0. 1 N HCl is 0. 001 mg/mL at 25 C. Each 250 mg lapatinib film layered tablet includes 398 mg lapatinib ditosylate equal to 250 mg lapatinib free base. The inactive ingredients of lapatinib tablets are: FD & C Yellow 6/Sunset yellow FCF Aluminum lake, hypromellose, lecithin, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, polyvinyl alcohol, povidone, sodium starch glycolate, talc, titanium dioxide, xanthan periodontal. Lapatinib is used together with letrozole to treat postmenopausal women with hormone-receptor positive and HER2-receptor positive metastatic breast cancer. Lapatinib belongs to the group of medicines called antineoplastics. It disrupts the growth of cancer cells, which are at some point damaged. Since the growth of normal cells may also be affected by the medication, other undesirable impacts will also occur. A few of these may be significant and need to be reported to your physician. This medication is offered only with your medical professional's prescription.
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