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Lassa Fever

Summarized by Plex Health
Last Updated: 13 May 2022
diagnostic proficiency and reporting of lassa fever by physicians in osun state of nigeria. "diagnostic proficiency and reporting of lassa fever by physicians in osun state of nigeria.", by Olowookere SA, Fatiregun AA, Gbolahan OO, Adepoju EG. F1: Graded score on Lassa fever knowledge....

Lassa fever is an acute viral haemorrhagic health problem triggered by Lassa virus, a member of the arenavirus family of viruses. Among patients that are hospitalized with serious medical presentation of Lassa fever, case-fatality is approximated at around 15%. About 80% of people who become contaminated with Lassa virus have no symptoms. The incubation period of Lassa fever ranges from 2, 21 days. Because the symptoms of Lassa fever are non-specific and so different, medical diagnosis is typically difficult, particularly early during the disease. Lassa fever is challenging to distinguish from other viral haemorrhagic high temperatures such as Ebola virus disease, malaria, shigellosis, typhoid fever and yellow fever. A lot of the moment, the Lassa fever virus causes only mild symptoms like fever and headaches. A type of rodent called the multimammate rat brings the Lassa fever virus in its pee and poop. People risk capturing Lassa fever from infected rats if they: Come into contact with the rats' pee or droppings; Catch and prepare the rodents as food; Breathe in tiny airborne particles contaminated with the rats' poop. It's unusual, yet feasible, to get Lassa fever from an individual who is sick with it. The Lassa fever virus can spread out via infected medical equipment, like recycled needles. Nearby nations are additionally in danger due to the fact that the animal vector lives throughout the area. The first documented case took place in 1969. Lassa fever is named after the town in N..ia where the first cases happened. About 100,000 to 300,000 infections of Lassa fever occur each year, with about 5,000 fatalities. Surveillance for Lassa fever ranges locations so these estimates are crude. In some areas of Sierra Leone and Liberia, about 10-16% of people confessed to healthcare facilities every year have Lassa fever. This reveals the severe influence the disease carries the region.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
135357333C23H21N5O2399.4CN1C=C(C2=C(C1=O)NC(=C2)C3=CN(N=C3)C)C4CC45C6=CC=CC=C6N(C5=O)CCN1C=C(C2=C(C1=O)NC(=C2)C3=CN(N=C3)C)[[email protected]@H]4C[[email protected]]45C6=CC=CC=C6N(C5=O)CInChI=1S/C23H21N5O2/c1-26-12-15(14-8-18(25-20(14)21(26)29)13-10-24-27(2)11-13)17-9-23(17)16-6-4-5-7-19(16)28(3)22(23)30/h4-8,10-12,17,25H,9H2,1-3H3/t17-,23-/m0/s1PEMNGSWIBJARND-SBUREZEXSA-N(1R,2S)-1'-methyl-2-[6-methyl-2-(1-methylpyrazol-4-yl)-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl]spiro[cyclopropane-1,3'-indole]-2'-one0.9399.16952493399.1695249374.281301323002200001
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