Leber Hereditary Optic Neuropathy

Summarized by Plex Health
Last Updated: 05 May 2022
leber hereditary optic neuropathy: current perspectives. "leber hereditary optic neuropathy: current perspectives.", by Meyerson C, Van Stavern G, McClelland C. f2-opth-9-1165: Right optic nerve (A) of a patient with acute LHON-related vision loss showing mild hyperemia, blurring of the disc margin, and elevation of the optic nerve head from swelling of the peripapillary retinal nerve...

Leber hereditary optic neuropathy is an inherited type of vision loss. Blurring and clouding of vision are usually the first symptoms of LHON. These vision issues might start in one eye or simultaneously in both eyes; if vision loss begins in one eye, the other eye is usually affected within numerous weeks or months. In time, vision in both eyes gets worse with a severe loss of intensity and color vision. Vision loss arises from the death of cells in the nerve that communicates visual information from the eyes to the brain. Central vision progressively boosts in a small percentage of cases, in most cases the vision loss is permanent and profound. Vision loss is usually the only symptom of LHON; nevertheless, some families with extra symptoms and signs have been reported. Along with vision loss, the features of LHON plus can consist of movement disorders, tremblings, and problems of the electric signals that manage the heartbeat.

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