Lenalidomide

Summarized by Plex Health
Last Updated: 02 May 2022
lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity. "lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity.", by Leuci V, Maione F, Rotolo R, Giraudo E, Sassi F, Migliardi G, Todorovic M, Gammaitoni L, Mesiano G, Giraudo L, Luraghi P, Leone F, Bussolino F, Grignani G, Aglietta M, Trusolino L, Bertotti A, Sangiolo D. Fig5: Combination of Lenalidomide-5FU reduced mCRC proliferation index. a The combination of lenalidomide and 5FU significantly reduced Ki67 proliferation index in mice with mCRC tumorgraft (N = 6), compared to controls treated with 5FU (N...

Lenalidomide is used to deal with numerous myeloma, either in combination with another medicine or after stem cell transplant. Lenalidomide might cause blood clots. Lenalidomide can cause severe, serious birth defects or death of an infant if the mommy or the dad is taking lenalidomide at the time of fertilization or throughout pregnancy. If your period is late while taking lenalidomide, tell your physician right away. For Women: If you have not had a hysterectomy, you will be required to use 2 reliable forms of birth control starting 4 weeks before you begin taking lenalidomide and finishing 4 weeks after you quit taking it. Lenalidomide is a lotion to light yellow color powder. Lenalidomide is more soluble in natural solvents and low pH remedies. Lenalidomide has an asymmetric carbon atom and can exist as the optically active forms S and R, and is created as a racemic blend with a net optical rotation of absolutely no. Lenalidomide is readily available in 5 mg, 10 mg, 15 mg and 25 mg capsules for oral administration. Each pill consists of lenalidomide as the active component and the adhering to inactive components: anhydrous lactose. The pill covering ingredients common to all staminas are gelatin and titanium dioxide. Lenalidomide is only readily available as part of a special program called Revlimid REMS. Lenalidomide is being studied in the treatment of other problems and types of cancer. Definition from the NCI Drug Dictionary, Detailed scientific interpretation and other names for this drug. Drugs are usually examined to figure out if they can assist deal with or protect against problems besides the ones they are authorized for. This patient information sheet applies only to authorized uses of the medicine. Drug Shows Promise in Slowing Progression of Smoldering Myeloma to Cancer.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
216326C13H13N3O3259.26C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3NC1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3NInChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)GOTYRUGSSMKFNF-UHFFFAOYSA-N3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione-0.5259.09569129259.0956912992.543702411901010001
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