Leucovorin

Summarized by Plex Health
Last Updated: 08 May 2022
remarkable response to fluorouracil, leucovorin, oxaliplatin, and irinotecan therapy in urothelial cancer of the renal pelvis: a case report "remarkable response to fluorouracil, leucovorin, oxaliplatin, and irinotecan therapy in urothelial cancer of the renal pelvis: a case report", by . Fig1: a, b Abdominal computed tomography scan demonstrating the volume of renal pelvic tumor before treatment (a), and the decrease in volume after two cycles of fluorouracil, leucovorin, oxaliplatin, and irinotecan (b). c, d The...

Folic acid aids your body fruit and vegetables and maintain new cells, and aids avoid changes to DNA that might lead to cancer. Leucovorin is used to minimize the side effects of large doses or unintentional overdose of medications that can reduce the impacts of folic acid in the body. Leucovorin might additionally be used for functions not detailed in this medication guide. If you have destructive anemia or other types of anemia triggered by an absence of vitamin B12, you must not take leucovorin. If you have destructive anemia or other types of anemia caused by an absence of vitamin B12, you ought to not take leucovorin. There are many other drugs that can connect with methotrexate and reduce your body's capability to process and remove the medication. Leucovorin is usually supplied other medicines to assist your kidneys remove methotrexate from your body. You will require constant medical tests to help your doctor establish how much time to treat you with leucovorin.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
135403648C20H23N7O7473.4C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)OC1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[[email protected]@H](CCC(=O)O)C(=O)OInChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12?,13-/m0/s1VVIAGPKUTFNRDU-ABLWVSNPSA-N(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid-1.2473.16589610473.16589610216911071093402110001
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