Levetiracetam

"levetiracetam reverses synaptic deficits produced by overexpression of sv2a.", by Nowack A, Malarkey EB, Yao J, Bleckert A, Hill J, Bajjalieh SM. pone-0029560-g005: Effects of SV2-EGFP expression and levetiracetam treatment on synaptic levels of SV2 and synaptotagmin.A) Neuronal processes labeled with an antibody against SV2 (all isoforms) revealed punctuate immunofluorescence along the lengths of the processes. Labeling...

Levetiracetam is used alone or along with other medications to assist manage specific types of seizures in the treatment of epilepsy. The chemical name of levetiracetam, a solitary enantiomer, is - ethyl-2oxo-1pyrrolidine acetamide, its molecular formula is C8H14N2O2 and its molecular weight is 170. 21. Levetiracetam is chemically unrelated to existing antiepileptic drugs. It has the adhering to structural formula: Levetiracetam is a white to beige crystalline powder with a faint odor and a bitter taste. It is very soluble in water. It is freely soluble in chloroform and in methanol, soluble in ethanol, sparingly soluble in acetonitrile and practically insoluble in n-hexane. Levetiracetam extended-release tablets, USP have the labeled quantity of levetiracetam, USP. Non-active components: colloidal silicon dioxide, microcrystalline cellulose, magnesium stearate, hypromellose, povidone, opadry white. Opadry white contains hypromellose, titanium macrogol, talc and dioxide. The medicine is combined with a medication release controlling polymer that provides a medication launch at a regulated rate. The biologically inert components of the tablet might occasionally remain undamaged during GI transit and will be eliminated in the feces as a soft, hydrated mass. This product fulfills the requirements of USP Dissolution Test 2.

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