Low-Grade Glioma

Summarized by Plex Health
Last Updated: 04 May 2022
circulating anti-filamin c autoantibody as a potential serum biomarker for low-grade gliomas. "circulating anti-filamin c autoantibody as a potential serum biomarker for low-grade gliomas.", by Adachi-Hayama M, Adachi A, Shinozaki N, Matsutani T, Hiwasa T, Takiguchi M, Saeki N, Iwadate Y. F2: Immunohistochemistry (IHC) for FLNC among normal brain, low-grade glioma and high-grade glioma. (A) FLNC protein expression level was higher in high-grade glioma (e, f) than in low-grade glioma (c, d) which expressed significantly higher...

Gliomas are a type of brain or spine tumor formed from glial cells. Glial cells are non-neuronal cells or non-nerve cells in the central nervous system. Once identified, a glioma is graded based on how abnormal the cells show up and just how promptly they are dividing or expanding. Quality I or quality II gliomas are considered low-grade gliomas. The name of the tumor usually describes the type of glial cell it originates from. Pediatric low-grade gliomas are the most common central nerves tumor in children. They compose 30% of all youth CNS tumors. The symptoms connected to low-grade gliomas can differ based on the size of the tumor as well as where it remains in the brain. A biopsy is a surgical treatment done to get an item of the tumor in order to detect the tumor by type and quality. A resection is a surgical procedure carried out to get most or all the tumor removed. Chemotherapy, is a medicine provided after surgical treatment to kill cancer cells or stop them from dividing and growing. Instances of chemotherapy generally used in low quality gliomas are vincristine, lomustine, vinblastine and carboplatin. This marker is the change in the cancer cell that makes it special from healthy cells. This therapy can keep cancer cells from expanding or repairing and can inform the cancer cell to destroy itself. The way the radiation is provided depends on the type of tumor, disease risk and where the tumor remains in the brain or spinal cord.

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