MELAS Syndrome

Summarized by Plex Health
Last Updated: 08 May 2022

MELAS syndrome is unusual disorder that begins in childhood, usually in between two and fifteen years old, and mainly influences the nervous system and muscles. Symptoms of MELAS syndrome usually begin in between the ages of 2 and fifteen years, yet delayed start cases have additionally been reported in between fifteen and forty years and late onset cases after forty years. Symptoms and physical findings linked with MELAS syndrome vary considerably between affected people in the same family and in between various families. The identifying feature in MELAS syndrome is the recurrence of stroke-like episodes. People with MELAS syndrome have a buildup of lactic acid in the blood, that can lead to vomiting, abdominal pain, tiredness, muscle weak point and trouble breathing. This accumulation of lactic acid has been kept in mind in the spinal liquid and in the brain. Individuals with MELAS syndrome may have episodes of confusion and hallucinations usually as a result of a coming before fever and/or headache.

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