Keep in mind that you will be prompted to visit or register an account. Information Restrictions Based On Area Of Research No. Commercial Use Specimen Restrictions No. Non-Genetic Use Specimen Restrictions Based On Area Of Use No. The primary goal of MSH was to figure out whether therapy with hydroxyurea titrated to optimum tolerated doses would lower the frequency of vaso-occlusive dilemmas by a minimum of 50%. Events of upper body disorder were counted as crises. The secondary goals checked out the correlations of fetal hemoglobin HbF degrees and other patient or treatment characteristics with the incident of vaso-occlusive unpleasant dilemmas, and the impact of therapy on the top quality of life.
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